Whole Exome Sequencing in Inherited Endocrine Disorders

Entire Exome Sequencing in Inherited Endocrine Disorders Foundation Atomic conclusion is significant in the administration of different pediatric endocrine issue including clutters of development, digestion, bone, hypoglycaemia and sexual turn of events. Customary PCR-based Sanger sequencing is the pillar group for atomic testing in pediatric cases. In any case, the enormous number of quality imperfections related with the different endocrine issue renders quality by-quality testing progressively costly and ugly. The enormous number of possibly significant qualities makes it trying for emergency clinic atomic analytic research centers to offer quality based testing everything being equal. Given the significant expenses related with single-quality tests, the determination of possibility for single-quality sequencing will in general be consecutive instead of comprehensive and equal. By and by, various qualities might be redistributed to various clinical or sometimes scholarly exploration research facilities which adds to the multifaceted nature. Utiliz ing new high-throughput sequencing innovations, entire genomes, entire exomes or applicant quality boards (directed quality sequencing) would now be able to be cost-viably sequenced for endocrine patients. Sooner rather than later, conventions including cutting edge sequencing would presumably be considered as a fitting part of routine clinical determination for significant patients. Imperfections of pituitary hormones lead to variations from the norm in development (e.g., short height), sexual turn of events, richness, stress reaction and other metabolic procedures. Various qualities coding for translation factors have been recognized, changes in which cause clinical scatters in people related with pituitary insufficiencies [1-2]. A portion of these elements, for example, PROP1, TPIT, POU1F1, LHX3 and LHX4, assume jobs in the ordinary embryological advancement of the foremost pituitary. Transformations in these qualities can prompt numerous pituitary hormone inadequacies or potentially syndromic hypopituitarism [3]. The interpretation factors, for example, HESX1, OTX2, SHH, SOX2 and SOX3 are engaged with midline advancement. Transformations in these can cause septo-optic dysplasia or holoprosencephaly, the two of which may incorporate pituitary hormone lacks [4]. Different qualities encode the antecedents to pituitary hormones (development hormone, ACTH [through handling of POMC], gonadotropic-luteinizing hormone and follicle-animating hormone, and thyroid-invigorating hormone). Transformations in these qualities lead to phenotypes normal for singular hormone insufficiency. The pituitary secretory cells themselves react to signals starting in the nerve center, some of which are likewise peptide hormones with explicit receptors communicated on the reacting cells; changes in these qualities or their related receptors can likewise cause joined or explicit pituitary lacks [1]. Be that as it may, numerous instances of inborn hypopituitarism despite everything stay unexplained and most are probably be cause of different causes, either transformations in other formative qualities or epigenetic impacts during embryogenesis. Short height is a typical introduction to the pediatric endocrinology facilities. Be that as it may, no reason is distinguished in a huge extent of patients who are delegated having idiopathic short height [5, 6, 7]. It is evaluated that the fundamental reason for short height stays obscure in around 80% of patients [8]. In an enormous scope pooled Next-Generation Sequencing study to recognize hereditary reasons for short height, 4928 hereditary variations in 1077 qualities were available in patients however not in control subjects [9]. Enormous scope sequencing endeavors can possibly quickly recognize hereditary aetiologies of short height. In another investigation, trying to distinguish known and hereditary reasons for short height by directing entire exome sequencing of the patients with serious short height and their relatives, hereditary reason for short height was found in 5 out of the 14 enrolled patients [10]. Uncommon hereditary deformities in the GH/IGF-1 pivot have been fo und to cause short height. A higher recurrence of uncommon CNVs (normal number variations) has been accounted for in patients with short height [8, 11]. An ongoing report to characterize hereditary characterisation of a companion of kids clinically marked as Growth Hormone or IGF1 coldhearted found that entire exome sequencing added to the analysis of kids with suspected development hormone and IGF1 heartlessness, especially in the Growth hormone uncaring subjects with low serum IGF1 SDS and stature SDS [12]. It might be presently conceivable to distinguish likely hereditary reasons for short height by executing genomic analytical strategies like entire exome sequencing in huge numbers of these youngsters who have obscure purposes behind their poor direct development. Innate Hyperinsulinism (CHI) is the most well-known reason for tireless and intermittent hypoglycaemia in early stages [13]. It is the aftereffect of unregulated insulin discharge from the pancreatic ÃŽ ²-cells prompting serious hypoglycaemia [13, 14]. This condition has been accounted for in about all significant ethnic gatherings and influences at any rate 1/50,000 offspring of European drop [14]. CHI is brought about by hereditary deformities in key qualities controlling insulin emission. The hereditary premise of CHI includes changes in nine distinct qualities (ABCC8, KCNJ11, GLUD1, GCK, HADH, SLC16A1, HNF4A, HNF1A and UCP2), which manage insulin emission from the pancreatic ÃŽ ²-cells [14,15]. The most widely recognized sub-atomic reason for CHI is the brokenness of the pancreatic KATP channel encoded by the sulfonylurea receptor quality (ABCC8) and the internal redressing potassium channel quality (KCNJ11) [14,15]. CHI can likewise be optional to chance elements like birth asphyxia, intra-uterine development hindrance, Rh isoimmunisation and maternal diabetes mellitus or related with different formative conditions [16]. Histologically, CHI can be related either with diffuse insulin discharge or with central adenomatous hyperplasia. Positron emanation tomography examine utilizing Fluorine-18 L-3, 4-dihydroxyphenylalanine (18-fluoro DOPA-TC-PET-filter) has been utilized to recognize central from diffuse structures. Clinical medicines of CHI incorporate diazoxide (KATP channel activator), somatostatin simple (octreotide) infusions, and suitable eating regimen. The careful treatment with subtotal pancreatectomy is required in diffuse CHI when clinical treatment and dietary treatments are ineffectual, though central CHI can be relieved with resection of the central territory of adenomatous hyperplasia [14, 15, 16]. As of late, mammalian objective of rapamycin (mTOR) inhibitor sirolimus has been util ized in treatment of relentless serious CHI not amiable to clinical treatments [18]. CHI has been depicted as a related finding in different conditions like Beckwith-Wiedemann, Kabuki, Trisomy 13, Mosaic Turner, Sotos, Usher, Timothy, Costello, Central Hypoventilation disorder and Leprechaunism (Insulin Resistance Syndrome) [17]. Be that as it may, in numerous patients, with clinically characterized syndromic highlights and with hypoglycaemia, no recognizable hereditary reason adding to hyperinsulinism is found. In an enormous arrangement of 300 patients, hereditary analysis was made distinctly in 45.3% of the patients and changes in ABCC8 were the commonest recognizable reason [19]. By far most of patients with Diazoxide-responsive CHI (77.6%) had no recognizable changes, proposing other hereditary components [19]. Atomic finding can be significant for clinicians to deal with the patients all the more viably and to advise guardians on the anticipation and illness repeat. Entire Exo me sequencing can be invaluable in these gatherings of patients to recognize the atomic deformities and to evaluate the coding variations that might be pathogenic in these patients [20]. Points To distinguish novel hereditary reasons for uncommon acquired endocrine issue in kids with an emphasis on innate hyperinsulinism, short height of obscure etiology and IGF1 variations from the norm by utilizing entire exome sequencing. Exploratory Design and Methods Persistent Recruitment Patients with a finding of CHI alluded to Alder Hey Children’s Hospital, which is a national referral community for CHI, will be selected into the examination. A composed educated parental assent will be gotten. These patients will be biochemically affirmed as CHI utilizing the accompanying rules: Blood glucose centralization of under 3.0 mmol/l with noticeable insulin as well as C-peptide Glucose necessity > 8mg/kg/min Low degrees of ketones and unsaturated fats during the scene of hypoglycaemia Clinical and biochemical information will be grouped from referral letter or by case note audit. Patients with an auxiliary reason for CHI, for example, perinatal asphyxia, intra-uterine development limitation, Rhesus isoimmunisation, newborn children of diabetic moms and babies with Beckwith Wiedemann disorder will be avoided from the examination. Patients are viewed as lethargic to clinical treatment if intermittent hypoglycaemia scenes ( Patients going to the Pediatric Endocrinology facility at Alder Hey Children’s Hospital with serious short height (>3 SDS beneath mean) for age and sex in whom the standard clinical work up has not uncovered an analysis for their short height will be enlisted into the examination. Patients alluded or assessed for development hormone lack of care (development disappointment, low serum IGF1 and ordinary/raised serum GH) or IGF1 inhumanity (pre-and postnatal development disappointment related with moderately high IGF1 levels) will likewise be enrolled into the investigation. A composed parental educated assent will be acquired preceding the enrollment. Entire Exome Sequencing (WES) WES will be performed at the Center for Genomic Research (CGR) based at the University of Liverpool. The test will be requested subsequent to clarifying the dangers and advantages of testing to the patient and acquiring composed educated assent. Every patient (and their folks or gatekeepers) will be instructed with respect to the expected revelation of conditions random to the sign for testing that may warrant treatment or extra clinical reconnaissance for the patient

Strategic Accounting Essay Example | Topics and Well Written Essays - 1500 words

Vital Accounting - Essay Example One of the significant improvements in the zone of administrative bookkeeping is the item life cycle costing which has increased genuine acknowledgment during late periods to address the difficulties of changes in the creation frameworks and methodology. Item life-cycle costing being the new advancement in the administration bookkeeping framework has been characterized as another region of detailing in cost the board frameworks which is the aggregation of expenses for exercises that happen over the whole life pattern of product(Hilton, 1994, p.230). Item life cycle looks at the life of the item from its advancement stage to the phase till the expulsion of the item from the utilization. As per Horngren and Foster (1991), item life-cycle covers the life of the item from the hour of introductory innovative work to when deals and backing of the item to the clients is pulled back. Burstein (1988) sees that the existence cycle costing turns out to be increasingly essential and significant in the light of fast changes in innovation and the shortening of the item life cycle. There is a sharp differentiation between the item's life cycle costs and the entire life cycle costs. Life cycle costs spread all the costs that the maker should cause and entire life cycle cost incorporates the expenses because of the customer like establishment, activity, support, rejuvenation and removal (Shields and Young 1991.) Adamany and Gonsalves (1994) have distinguished the accompanying seven phases in the existence pattern of an item: 1. Examination Stage - including a basic appraisal of the idea and the impacts of contributing on the idea 2. Start Up Stage - involving prototyping, devotion of the assembling offices and pragmatic appraisal of the impacts of the speculation 3. Section Stage - where the passage into the market with another item or administration is arranged 4. Development Stage - during which the firm gets back the profits on speculation as potential deals incomes 5. Development Stage - at which the firm collects the benefit from the item or administration 6. Decrease Stage - connoting the altering down of the business which requires moving to the withdrawal stage or renewing the item 7. Withdrawal Stage - the item is pulled back from the market It is additionally fundamentally significant that the directors assemble all the necessary data at the various phases of the existence cycle and the existence cycle idea acquaints a coordinated methodology with arranging and planning. Mapping of Key Information Requirements Life Cycle Phase Time Client Requirement Fulfillment Target Estimating Asset Necessity Consistent Enhancements Income Examination Basic Basic Basic Basic Basic Start up Basic Basic Basic Basic Basic Section Basic Basic Basic Basic Basic Development Basic Basic Basic Basic Basic Basic Development Basic Basic Basic Basic Decay Basic Basic Withdrawal Basic Source: (Adamany and Gonsalves 1994) Activities under Life Cycle Costing for Generating Revenue and Reducing Costs Income Generation Cost Reduction Item Improvement: New Processes Highlights Aggregate Volume Execution Experience

Transitional Birthday free essay sample

Transitional Birthday I gaze vacantly at myself in an old and filthy mirror. Consistently I some way or another end up in my parents’ restroom upon the arrival of my birthday. Today is my thirteenth birthday celebration. As I gaze into the mirror, I understand that I am found to develop. I can’t envision life as an adult. What's more, my folks stroll into their washroom where I am standing and shout, â€Å"Wow! Marlee turns so become upward! She is getting so old!† My father folds his arms over me and gives me a colossal giant squeeze. Tears gradually move down my cheeks as I cry. I recall to past times worth remembering, primary school years, when life was indiscreet and free. All the neighbor children would accumulate in my yard and we would make up the most arbitrary games to play. Now and then we would even set up our own Olympics. We will compose a custom article test on Transitional Birthday or on the other hand any comparable point explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page Presently numerous individuals might be comfortable with the genuine Olympics, yet our rendition was an entire diverse story. Two individuals would be on bicycles and they would race around the square attempting to beat the other individual to the focal point of the square. We would play this for quite a long time. The individual who won the most races got the gold decoration which was a treat. We would likewise play a definitive round of find the stowaway; it was find the stowaway tag. Due to all the labeling and pushing, there were neighbor kids on the ground at regular intervals, that’s how extraordinary it was. Here and there the young ladies and I in the area would get together and put on spruce up garments and the most revolting make-up ever. In the wake of getting excellent, we would sing into these chimney utensils (used to move the kindling) to melody we as a whole know for instance, â€Å"Shape of my Heart† by Backstreet Boys. Once in a while we would even tape it and watch it later (our exhibitions were unquestionably a sight to see). My father was in every case some portion of the pleasant activity. At the point when I was three, he would give me the best horsy rides ever. All I would need to state was, â€Å"Daddy, horsy!† And he would know immediately what I needed. I would ride on his back, while he was slithering with me on him, for quite a long time. I would giggle and chuckle and have the best time on the planet. The horsy rides consistently made me upbeat and the best part was toward the finish, all things considered, my father would state, â€Å"Whoa, I’m tired, you piggy.† My return would be, â€Å"I’m not a piggy, daddy!† As my mother gives me a Kleenex and I settle down, she discloses to me how growing up will be a great encounter. She enlightens me regarding her high school years and all that she encountered in her life. What's more, obviously as each mother does, she raised marriage. She says how she can’t stand by to see me get hitched and have a family. I simply answer, â€Å"Okay mother, alright I get it.† It is then that I understand that growing up won’t be so terrible. I will get the chance to begin my own family and own a house. I will get the opportunity to encounter new things and gain proficiency with the estimations of life. I likewise understand that I just grew up a little in my parents’ restroom since when I was a child I was terrified yet as a young person I am energized and prepared. The exact opposite thing my mother and father say is, â€Å"All these things that happen today and tomorrow and in three years will shape who you are in the future.† As they exit, I gaze in the mirror indeed, and this time I don’t see a kid I see a young person growing up.

Commentary Moon Tiger, 1987, by Penelope Lively Free Essays

- Make notes on wellbeing - Make contextual investigation notes on hydrology and coasts - Do past inquiries on coasts hydrology - Do sonnet article - Plan kinder vehicle exposition Commentary: Moon Tiger, 1987, by Penelope Lively This monolog delineates the contemplations of an old lady who is biting the dust in a medical clinic. She gives us a her perspectives and depiction of language which shows us the significance it holds throughout her life. She discusses the historical backdrop of language saying ‘we open our mouths and out stream words whose family lines we don't have the foggiest idea. We will compose a custom paper test on Discourse: Moon Tiger, 1987, by Penelope Lively or on the other hand any comparable point just for you Request Now ’ This shows she thinks incredibly about words and their inception and her that more individuals care about it too. The rhyming of ‘flow’ and ‘know’, may likewise have a comical impact as it recommends that she is playing with the words. She additionally utilizes symbolism to depict what words resemble saying they ‘blow with the breeze, sleep, stir, cover parasitic on the most impossible has, endure and endure and survive’. She represents language, contrasting it with a creature or a plant that doesn't bite the dust however rejuvinates. This demonstrates how firmly she feels about language. She portrays it as being eternal as it will never end. This may give an understanding with respect to how she may feel about biting the dust. She might need to endure her sickness, consequently the reiteration of ‘survive’. The reiteration of this word attracts accentuation to it. She may would like to live on through her words. She keeps on looking at language, utilizing representations, to different parts of nature, for example, when she says ‘it resembled grains of sand on the shore, the leaves on the incredible debris outside my window, vast and unconquerable’. The utilization of the similies gives us a picture of how immense and huge language is as the decription portrays how immortal and unlimited words are. She likewise utilizes the solid descriptors, ‘immeasurable’ and ‘unconquerable’ and how much force language holds to her and possibly how she feels when she utilizes it. She portrays individuals as ‘walking lexicons’, generalizing them. This may demonstrate that she thinks more about language than individuals and proposes that she accepts that words significantly affect people’s lives and shows the significance of it to her. Through this we get a decent feeling of her character. We see that she is a significant glad individual. We get flashbacks of her life as a youngster when she is ‘gloating over Gordon who ould not spell ANTIDISESTABLISHMENTARIANISM, the longest word in the dictionary’. This shows how pleased she is of her insight into language as she holds it over others. She additionally puts accentuation on the word which reveals to us progressively about how certain she is regarding the matter. She gathered names of st ars and plants, for example, ‘Arcturus’, ‘Betelgeuse’ and ‘toadflax’. These words are not basic to go over and may likewise recommend how priggish she is about the amount she knows on language. Essentially, it might show how unrivaled she feels knowing this data. It is her leisure activity to gather words which shows the significance of it in her life. Another flashback we get of her is the point at which she is dealing with her little girl as a youngster. These flashbacks give us a feeling of her backstory and her character. She admits to herself that she is anything but a decent mother and uses the word ‘repellent’ to portray her emotions towards youngsters. This is a significant solid antagonistic word to use towards youngsters as a great many people love kids and wouldn’t depict them along these lines. It is additionally an extraordinary complexity to the manner in which she discusses words and language. She discusses ‘the fervor of language’ and how it is ‘immeasurable’ and ‘inconquerable’. She plainly doesn’t feel indistinguishable path about kids from she depicts them as ‘boring’ and ‘distracting’. She gets restless with her young little girl, remedying ‘the inanities’, who is scarcely ready to articulate words accurately. She utilizes plosives, saying , ‘There are no such things as bow-wows and well gees’. This shows she is gettig enraged by a minor issue with language and gives her narrow mindedness. It likewise shows that she is a harsh individual. We are caused to feel thoughtful for her toward the start of the concentrate as she says, ‘Today language abandonned me’. This show how abandoned she feels without having the option to review as much about language as she used to. She alludes to it how she would allude to a companion that had left her. She proceeds on ‘staring into a void’, whih stresses how vacant and forlorn she feels without it. She begins to list words, ‘vase, cupoard, window, cutain’, which likewise features the frenzy she feels when she can't recall straightforward words. Language has been her solid suit through life, #her diversion and her companion and now it has ‘abandonned’ her, she feels powerless. Instructions to refer to Commentary: Moon Tiger, 1987, by Penelope Lively, Papers

Questions - Program Evaluation Method Essay Example | Topics and Well Written Essays - 1250 words

Questions - Program Evaluation Method - Essay Example (Julian, 1997) 1. Targets, exercises, result proportions of the rationale model possibly hazy or missing. This is on the grounds that rationale models contain arrangements of every one of the components of a rationale model without indicating which thing on one rundown is identified with which thing on another rundown. This can without much of a stretch lead to disarray in regards to the relationship among components or result in inadvertent exclusion of a thing on a rundown of components. 2. To an extreme (or excessively little) data possibly gave on the rationale model. The rationale model ought to incorporate just the essential components identified with program/venture structure and activity. When in doubt, it ought to give the master plan of the program/extend and abstain from giving quite certain subtleties identified with how, for instance, mediations will happen, or a rundown of the considerable number of organizations that will serve to improve joint effort endeavors. 3. Goals possibly mistook for exercises. The task evaluator must make surethat things recorded as goals are in certainty destinations as opposed to exercises. Anything identified with program execution or an undertaking that is being completed so as to achieve something is an action as opposed to a target. For instance, recruit 10 staff individuals is a movement that is being completed so as to achieve a target, for example, improve reaction time for approaching calls. Despite the fact that it forgets about data, a great model speaks to those parts of an activity that, in the perspective on the partners, are generally significant for seeing how the exertion functions. The engineers will experience a few drafts before creating at a form that the partners concur precisely mirrors their story. In the event that the data will turn out to be excessively unpredictable, it will be conceivable to make a group of related models, or settled models, each catching an alternate degree of detail. One model could outline out the expansive

Business Communication Portfolio Assignment Example | Topics and Well Written Essays - 1000 words

Business Communication Portfolio - Assignment Example Despite the fact that the possibility of amusement at Disney Land is commonly alluring for kids however it is introduced so that individuals from everywhere throughout the world appreciate visiting it (Jackson, 2011, p.139). In Hong Kong, it has been worked with fuse of International Theme Parks Ltd, The Walt Disney Company and the Hong Kong Government (Hong Kong Disneyland, 2013). The association is consistently expanding its alluring spots while improving the general amusement experience. Tremendous business portfolio regularly produces extraordinary challenges for Disneyland which in this manner influences consumer loyalty and long haul relations with different organizations. For example, on ends of the week or open occasions the parks become stuffed which causes enormous challenges for the guests. This paper plans to introduce two business-business letters identified with Hong Kong Disneyland. Horizon Event Management Company 26th Street, across Southern Avenue Hong Kong October 12, 2013 Mr. Robert James The Operations Manager Disneyland Resorts Hong Kong Subject: Complaint for poor hotel administrations. Dear Sir, On October 10, 2013, the understudies of Foundation School grade 4 to 6 visited the Hong Kong Disneyland Resort alongside the educators and other staff individuals. It was a school trip essentially masterminded to improve the imaginative feeling of understudies while empowering them to comprehend various stories. Also, to assist them with picturing the old style characters they have been finding out about since youth. Our point was to engage youngsters through most ideal methods. Nonetheless, the understudies didn't discover Disneyland as engaging as it has been showcased (Haberer, 2010, p.4). A large portion of the staff individuals griped about the mischief of representatives particularly the individuals who have been on obligations in the Toy Story Land. Subsequently I wish to whine about the poor administrations that the school has gotten fro m the eminent Walt Disney Company. The visit was masterminded by Skyline Event Management Company. In the wake of visiting the amusement parks, understudies were required to compose an extensive survey of the whole outing. This was done so as to increase inside information about their discernment and thoughts identified with various animation characters. Also, they were expected to form stories with the assistance of their preferred kid's shows. They were additionally asked by the occasion directors to fill the criticism structures with respect to the whole outing. The criticism structures which we got were sufficiently huge to tell us about the poor administrations of your staff individuals. Understudies were profoundly de-spurred and even a portion of the guardians grumbled to the school the board with respect to the outing. Guardians were an excessive amount of worried about their children’s wellbeing. The majority of them accepted that the entertainment meccas and rides a t Disneyland were undependable for little youngsters. Here, I might want to include another significant thing that since Disneyland is promoted basically to the kids then why the administration has introduced such hardware which is unmistakably hazardous for youthful ones? Additionally, the more established individuals visiting Disney Land carry on discourteously with the little youngsters while then again, the overseeing staff for the most part don't react to the client grumbles. Indeed, even today I needed to hang tight for around two hours to meet you and at long last I was informed that you are occupied in some gathering and would not be accessible until one week from now. Every one of these things have enormously baffled us and thus I demand you to prepare you staff individuals while guaranteeing that more seasoned

What It’s Like To Intern At McKinsey

What It’s Like To Intern At McKinsey by: Andrea Carter on July 30, 2018 | 0 Comments Comments 10,240 Views July 30, 2018Abigail DeVito is a rising senior at Villanova School of Business interning with McKinsey Company this summer. Courtesy photoComing from Villanova University, a non-Ivy League institution,  Abigail DeVito confesses she was somewhat intimidated when embarking on her summer internship with the firm. McKinsey Company is one of the most prestigious management consulting firms where only the best of the best are known to work. Going in, she may have subconsciously expected an elitist bunch and wondered if maybe even her capability to do the work would be questioned. Instead, what she says she encountered was a pleasant revelation.â€Å"Everyone is humble, DeVito says. Once you’re there, everyone is a part of the community working on the same issues. I was very pleasantly surprised and happy to see that everyone was really, really humble about thei r education. There’s school spirit, but no one’s talking about it to rub it in your face.†Ã‚  Fears that her background would potentially be perceived as less than because she didn’t come from Harvard, University of Pennsylvania, or some other Ivy school were uncorroborated.  The fact of the matter was that DeVito, now a rising senior at the Villanova School of Business, was there. Last fall, the management information systems major had conquered McKinsey’s challenging, five-week long interview process which included an assessment exam that she likens to a mini SAT, a first-round interview, and a final round. Within hours of her final round, they had extended her an offer to join the firm as a summer business analyst in its digital practice. The invitation aligned nicely with DeVito’s passion for technology and her love for strategy. With that — in June of this year — she set out on a 10-week summer internship with one of the most esteemed consulting firms in the world.WHAT HAPPENS IN VEGAS Each week, DeVito boards a plane to Las Vegas where she spends Monday through Thursday working with her client. For client confidentiality reasons, she was unable to disclose the name to PoetsQuants. Details that were permissible were that the client is in the gaming and entertainment industry and they’ve turned to McKinsey to help achieve having 50% women in management roles by 2025 across the entire company.Together, DeVito’s team of four — herself, an engagement manager, one associate partner, and one senior partner — are creating a strategy and roadmap of activities to help the company achieve their goal.â€Å"I have been working on quantitative and qualitative analysis to identify gaps in opportunities, she says.  For instance, where are women in the organization today? What policies and processes does the employer currently offer?†DeVito adds, â€Å"I would say that for all of our work streams, it is very collaborative between me and my manager, but my ownership involves tracking of metrics of how we’re doing, analyzing the gaps and opportunities I mentioned, and getting a general sense of gender diversity in the organization as a whole. I also have client-facing experience with VPs and above almost every day.†At the end of each week, DeVito returns back to the East Coast to her home office that’s based in Jersey City.CLASSROOM PREP THAT MADE A DIFFERENCEThough it’s her first time inside a consulting firm, this isn’t DeVito’s first time working with a client producing strategy recommendations to achieve a company goal. Thanks to a flagship course at Villanova’s business school called Competitive Effectiveness, she’d done similar work with Ford Motor Company. The class pairs undergraduates with executives at local and regional companies to work on real problems.â€Å"Our task was marketing one of t heir cars to millenials in the Philadelphia area,† remembers DeVito. â€Å"The whole semester, the class teaches you how to learn and apply these marketing and management tools. At the end, you present a 50-page plan to the client and class.†DeVito says the course opens students’ eyes to consulting and she credits the experience with helping her prepare for her McKinsey interviews.WANT TO GET INTO MCKINSEY? HERE’S WHAT YOU SHOULD KNOWThere are two parts to interviewing with McKinsey, DeVito says. One is a case study, the second is a personal experience interview known as PEI. For the PEI, candidates are asked to share a previous personal experience in a team setting. â€Å"What they’re really looking for is your role on a team and what you did, she says. It’s uncomfortable to prepare for that because it sounds like you’re bragging. The most important thing is to be yourself, but really understand the impact you had in any story you te ll.† Page 1 of 212 »

Odyssey Essay Topics - Things to Consider When Creating Your Essay Topics List

Odyssey Essay Topics - Things to Consider When Creating Your Essay Topics ListOdyssey Essay topics are quite important for those students who aspire to earn their C or higher in SAT or ACT. A good list of topics helps one to concentrate on one area of interest and shows the reader that you care enough to promote yourself as a writer. It also gives them an idea of what type of material you can cover and how you can present it in an interesting way.With such topics, you will also be given a much better chance to remember those things that you need to cover. You will be able to speak about it in detail and get all the details right. By having all your essentials covered, you will have a more clear picture of your future writing abilities. In addition, having an outline to use will give you a sense of completion when it comes to that essay that you wrote.Certain topics are most likely to be covered but there is a big possibility that you will not be able to cover all your bases. In such situations, it is best to create a list of topics that you can use.Some of the various topics that are good to use are: Self-Development, Careers, Making a Good First Impression, Research, and Honors, Relationships, Career Planning, and Breaking the Ice. The topic categories are therefore easier to write and you can focus your attention on each area without forgetting any other aspects.One important thing to note is that when you search for topics online, you will get a list of topics that are already in existence. In this case, you will simply need to type a keyword phrase such as Odyssey Essay Topics into your search engine and then choose the one that fits best with your essay topic.It will be advisable to research which types of essays that you will be required to write in order to prepare for oral board exams. It is not unusual for students to use more than one type of essay format in order to be able to pass their exam. The question is, though, which type of essay format to us e?It would be best if you ask around or get advice from other students to see that essay type they find most efficient for college essay questions. They might just be glad to offer their feedback. So make sure that you give them a hand.

Sample Letter For Wayne County Economic Development...

Throughout my time interning for Wayne County Economic Development Corporation I spent many of my opening hours in a office doing research, analyzing data, writing memos, creating the entire system of how the corporation organizes and shares information, along with sitting in on meetings ranging from development of parcels to legal matters. From the beginning my supervisor continuously stated that this is a learning process and that he had hired all three interns to instill and familiarize us to what world is like outside of school classrooms and the library. After a few weeks on getting to individually know each intern I was selected for a special work load that only I would be sanctioned to work on to see my potential, as I was informed.†¦show more content†¦Before I was a junior at Michigan State University with only one prior internship at working as a legislative intern to working in the heart of Detroit underneath the some of the most influential people in the state of Michigan and a job that I solely there to help Michigan flourish back to what it used to be in the early 50’s. My internship entailed a lot of out three students two of which from MSU and the other from Wayne State. Its was a regular eight o’clock to four o’clock job, driving to work itself was an everyday objective from my established residency in Northern Oakland County roughly 40 miles each way. The three of us maintained our own quarters on the 28th floor of the Guardian Building in the financial district of Detroit where we could provide help to each other and work together to draft memos for the Mayor of Detroit Mike Duggan and CEO Warren C. Evans, business proposals for foreign counties to invest in Detroit and Wayne County, and creating a cloud based systems that each employee can import and export data from their current assignment with ease. Individually I was given the opportunity to set up and meet with all 43 communities within the borders of the c ounty. Where the Executive Director of Corporate Affairs and myself would ask questions that focused primarily on business retention and future devolvement. Interviewing and traveling to each city on a daily basis turned out to be the easiest part of the process. Communication was the most

How did leaders impact the civil rights - Free Essay Example

Sample details Pages: 2 Words: 739 Downloads: 5 Date added: 2019/03/22 Category History Essay Level High school Tags: Civil Rights Movement Essay Did you like this example? Purpose Statement The purpose of this paper is to explain the events and leaders that impacted the Civil Rights Movement. I became interested in this idea when I first started learning about it in social studies, I then decided to go very deep into it and It really interested me. Don’t waste time! Our writers will create an original "How did leaders impact the civil rights?" essay for you Create order The information gained from this paper will help people understand the past and be able to learn from their mistakes. This information can help people grow into better versions of themselves. Therefore, I wanted to research and find out more information leaders and their impact on the Civil Rights Movement. Methodology Statement I began by scouring the internet and found the Civil Rights Movement and how long it was on The New Georgia Encyclopedia. I then, read the article and found out about the different people who helped and could be classified as leaders in the movement. I searched up each of their names and found articles on them, such as Martin Luther King Jr., John Lewis, and Malcolm X (etc.). I asked myself questions like; who are they? How do they show leadership? What did they do to impact the civil right movement? I began researching those question and came up with answers. Introduction According to The New Dictionary of Culture and Literacy the Civil Rights Movement is known as The national effort made by African Americans and their supporters in the 1950s and 1960s to eliminate segregation and gain equal rights (2005). Thats the dictionary definition of the Civil Rights Movement but, it means a lot of different things to a lot of different people. For example; for African Americans it was a time where they were fighting for equality, for white supremacists it was a time of fighting and hatred. There were those people who stood out among the rest and took up the role of a leader to gain rights and equality. There were those people who stood up for what they believed in and fought to the bitter end. Some of them didnt even see their goal accomplished but, they still tried. Research/Findings When people think Civil Rights, whats the first thing that pops into their head? Martin Luther King Jr. Well at least for most. For some people its segregation or other leaders. Leaders in this time were all shapes, sizes, and genders. Rosa Parks for example. John Lewis is another. John Lewis was always risking everything, including his life, for the Civil Right Movement. He fought battles, real and figuratively, always being arrested. He was part of Freedom Rides, which is where he and a small group of people would protest against the busses. Soon after, in 1963, he was given a place in the SNCC. This is a Civil Rights organization. Now he is a U.S. Representative for Georgias 5th congressional district. (Georgia Humanities and the University of the Georgia Press, 2004-2018) Elaine Brown is another great example. Elaine Brown was a chairwomen in the Black Panther Party. The Black Panther Party was made by Bobby Seale and was called the Black Panther Part only for self-defense. Elaine Brown was first introduced to the Black Panther Party when she started writing for the Black Congress Newspaper. They only then started to take notice of her when appeals for the Huey Newton Legal Defense Fund came in. It was long after in the end of April 1968 she went to her first official Black Panther meeting. She became the editor for The Black Panther. This was a huge achievement for her because after that she became the first elected female of the Panther central community. She helped lead other to do the same. (In the article, Brown, Elaine 1941-, 2017-2018). Martin Luther King Jr. A man who helped everyone and anyone. He believed the way to get his and others rights was to have peaceful protests and no violence. He participated from anything to protests to boycotts. After Rosa Parks refused to give up her seat on the public Montgomery bus people started to plan a boycott. Martin being the leader he was joined along with boycott. Originally the boycott was supposed to be one day but, it ended up being 381 days. Before the boycott Martin had been asked to join the MIA. He agreed and ended up leading the whole thing. The boycott still continued even though lots of people were being arrested.(Georgia Humanities and The University of the Georgia Press, 2004, 2018).

Biological Aspect Of Traumatic Stress Disorder ( Ptsd )

A father lost his son in 2014 to a terrible automobile accident. His last memory of his son was holding and kissing his sons lifeless body after the accident and listening to the coroner announce the death of his son. Since his death, this man has suffered from Post-Traumatic Stress Disorder (PTSD). The worst of his PTSD occurs at the same time every night in a reoccurring dream. He also has shown signs of aggression towards his family who are trying to help him. He’s always shown an aggressive side but this aggressive side is very mean and angry towards others. We’ll discuss the six theoretical models to describe his condition with PTSD. These six models are biological, psychodynamic, behavioral, cognitive, humanistic and socio-cultural. Firstly we’ll talk about the biological aspect of PTSD and his problem with his son. The biological model is typically a medical standpoint of PTSD and regards a brain with abnormal behavior. Some of the effects of biological mo del are head injury, poor nutrition, genetics, evolution, or viral infections. Some of the treatment could be psychotropic medications, electroconvulsive therapy, or neurosurgery. The man described above, has poor nutrition which could be the only symptom of the biological aspect. With more research, genetics, head injury, and other remaining factors could also be issues as well (â€Å"Abnormal Psychology†). Moving onto the psychodynamic model, this involves the unconscious aspect of PTSD. Experiments were conducted andShow MoreRelatedPtsd : Post Traumatic Stress Disorder1462 Words   |  6 PagesPTSD, post-traumatic stress disorder is a mental disorder or serious condition that can develop after a victim who has witnessed or experienced a traumatic event.(American Psychiatric Association, 2013) When PTSD was identified as an mental health condition by the psychologist? The term PTSD first appeared in the 1980s, but the concept of this disorder can be traced back to 1952 when the first edition of the Diagnostic and Statistical Manual of Mental Disorders, DSM was published. The stress reactionRead MoreChildhood Abuse Or Neglect And Genetically Such As Relative With Mental Health Problems1727 Words   |  7 Pagesintervention counselling, current use of psychotropic medication, type of trauma, time since the trauma and following traumatic event† (Karatzias et. al, 2013, p. 503). Not all trauma survivors will develop permanent PTSD disorders and some may be later on will be affected. The risk factors: environmental, demographic, prior psychiatric disorder, personality dimensions, dissociation, biological and cognitive risk factors. â€Å"In the end, the impact of an environmental event, such as a psychological trauma,Read MoreThe Consequences of Post-Traumatic Stress Disorder1621 Words   |  6 Pages Post-traumatic stress disorder (PTSD) is a medical condition that many people suffer from at different ages. Most of the people that have suffered from PTSD have done so due to a major trauma that occurred at some point in their life. Even though the trauma could have happened months or even years earlier, the symptoms can come back when an event or the anniversary of the trauma triggers the memory of the traumatic event. Some of the traumas that cause post-traumatic stress disorder are rapeRead More Post Traumatic Stress Disorder Symptoms and Treatment Essay1416 Words   |  6 PagesIn 1980, the term Post Traumatic Stress Disorder (PTSD) first came into existence in the Diagnostic and Statistical Manual of Mental Disorders, Third Edition (DSM-III). Only in 1987 did the DSM series make reference to traumatized children. The first major studies of the effects of large traumas on children were Blochs 1956 study of the effect of a tornado in Mississippi, Laceys 1972 study of the effects of an avalanche on a Welsh school, N ewmans 1976 work on the Buffalo Creek disaster and TerrsRead MoreUndoing the Adregenic Response to Treat PTSD1403 Words   |  6 Pagesexample of this is, of course, in trauma, and more specifically Post Traumatic Stress Disorder (PTSD). Understanding how these systems work synergistically and how they may be impaired is particularly important given the political reality that we have a generation of people going to war for multiple deployments. Repeated exposure to intense emotional stimuli and seemingly disturbed memory function are reflected in current rates of PTSD in returning soldiers, reportedly between 17 and 25 percent (DonovanRead MoreWhat ´s Post-Traumatic Stress Disorder? Essay852 Words   |  4 PagesWhat is PTSD? Post-Traumatic Stress Di-sorder is a syndrome exp-erienced by many veter-ans, and is a priority of a plethora of psychological researchers. The Diag-nostic and Statistical Man-ual of Mental disorders lis-ts eight criterion for this widespread mental dis-ease, including a stressor, meddling symptoms, ev-asion, amendments in provocation and react-ivity, and a duration of symptoms for more than a month. PTSD is often characterized by disrupt-ions in sleep patterns, with the traumatic eventRead MorePost Traumatic Stress Disorder (PTSD) Essay4334 Words   |  18 PagesPost Traumatic Stress Disorder (PTSD) has been the focus of considerable attention, and some controversy, since it was formally recognised in 1980 by the American Psychiatric Association. This essay will discuss the history of this relatively new diagnosis and its place within the DSM-IV-TR, whilst three perspectives of pathological reaction to trauma, namely, socio-cultural, psychological and biological factors will also b e compared. In conclusion this essay will discuss how the three perspectivesRead MoreThe Effects Of Post Traumatic Stress Disorder1494 Words   |  6 PagesCauses and Effects of Post-Traumatic Stress Disorder (Post-Traumatic Stress Disorder) Post-Traumatic stress disorder has affected humans probably as long as we have had a higher consciousness, but it is only recently that researchers, medical professionals and psychotherapists have had much understanding into its nature and treatment. Although this disorder may be easy to describe, the effects of Post-Traumatic Stress Disorder negatively affect a person’s mental health, physical health, work andRead MorePost Traumatic Stress Disorder ( Ptsd )962 Words   |  4 PagesPost-traumatic stress disorder (PTSD) is a relatively new name for a condition that has bedeviled veterans of the military service members throughout the history of warfare. It has taken people around the world, especially within the military branches an exceptionally long time to understand and face the reality of a growing epidemic known as Post-Traumatic Stress Disorder (PTSD). The best and ideal starting point to understand PTSD would be by raising the question, what is PTSD? According to physi ologicalRead MorePost Traumatic Stress Disorder ( Ptsd )1198 Words   |  5 Pages Post-traumatic stress disorder(PTSD) is a mental illness that is triggered by witnessing or experiencing a traumatic event. â€Å"PTSD was first brought to public attention in relation to war veterans, but it can result from a variety of traumatic incidents, such as mugging, rape, torture, being kidnapped or held captive, child abuse, car accidents, train wrecks, plane crashes, bombings, or natural disasters such as floods or earthquakes(NIMH,2015).† PTSD is recognized as a psychobiological mental

St. Petersburg The Myth and the City Essay - 646 Words

St. Petersburg: The Myth and the City In â€Å"The Nose† and â€Å"The Overcoat,† Gogol makes fun of the rank-conscious Russian society. In â€Å"The Overcoat,† he emphasizes the phony world of Russian officials, who are powerless mediators under a hierarchy in which each person fears his superior. Of the two stories, â€Å"The Nose† is lighter-hearted and more comedic. On the surface, it is a humorous story about a government official literally losing his nose and searching for it. For much of the time, Gogol makes fun at the official’s expense. In many passages much is stated comically about how stratified Russian society was at the time. Gogol skillfully portrays not just Kovalyov as being an self-important minor official, but also of Kovalyov’s†¦show more content†¦Ã¢â‚¬Å"The Overcoat† is a darker tale. It is a tale of a poor official and his abnormal pride in his incredibly shabby overcoat. However, it is also a reflection of Russian society. The introductory paragraphs paints a very grim picture of life. Once, in a department†¦but better not mention which department. There is nothing touchier than departments, regiments, bureaus, in fact, any caste of officials. Things have reached the point where every individual takes an insult to himself as a slur on society as a whole†¦ And so, once, in a department, there worked an official. This official was nothing much to speak of: he was small, somewhat pockmarked, his hair was somewhat reddish and he even looked somewhat blind. Moreover, he was getting thin on top, had wrinkled cheeks and a complexion that might be aptly described as hemorrhoidal. But that’s the Petersburg climate for you. (Gogol, 115) Readers have a very specific story told through a generic setting – with this setting presented as being necessary due to the nature of the agency for which this official worked without recognition. Gogol’s humor here is much less obvious than in â€Å"The Nose.† The official is shown to have much too great a pride in his poor, worn-out overcoat, and in is his efforts to get it repaired and theShow MoreRelatedSt. Petersburg: The Myth and the City Explained in Pushkin’s â€Å"The Bronze Horseman† and Gogol’s â€Å"Nevsky Prospect†689 Words   |  3 Pages St. Petersburg: The Myth and the City Pushkin’s â€Å"The Bronze Horseman† and Gogol’s â€Å"Nevsky Prospect† allow a deeper view into the history and lifestyle of St. Petersburg. Both stories exhibit the ambivalence that exists in many aspects of St. Petersburg. â€Å"Nevsky Prospect† gives us a view of the city of St. Petersburg. The majority of the story takes place on Nevsky Prospect, which appears to be a central place in St. Petersburg. This location gives readers insight into the daily lives and differentRead MoreNaming Famous Places1014 Words   |  4 Pagesof place-names? 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Marketing Research Processes-Case Study

Question: Describe the Marketing Research Processes? Answer: 1. Executive Summary This market research study was conducted to determine if Elegant magazine an exclusive luxury lifestyle magazine should expand its distribution region from UAE only into the entire GCC region. The research method uses a combination of qualitative in depth client interviews and quantitative research for competitor pricing and distribution numbers and reach. The results of the research study will be analyzed to answer the MDP "Should we expand our distribution to cover the entire GCC region?" for Elgant magazine. The study takes three components of the MRQ to derive interview questions. The research study explains the methodology used for the interviews, who and how the interviewees were selected. The summery of the results then is analyzed to determine whether it would be feasible for Elegant magazine to expand its distribution to cover the entire GCC region instead of the current UAE only distribution. The decision will be based on the perceived demand and projected financial gains. 2. Background Research Company name: Elegante magazine. History: Elegante magazine was founded in 2009 in Beirut Lebanon. In 2011 the publication was introduced into UAE. In November 2014 there were some management changes and an overall haul of the magazine. Nature of Business: Quarterly published Luxury lifestyle magazine, target audience are high net-worth individuals who are interested in luxury brands and items. The range covers UAE locals and expats, male and female readers between the ages of 35 to 60. The Elegante Magazine is engaged in covering the stories of celebrities, big business tycoons and youth figure of style. Location: IT Plaza, office 916, silicon oasis. Dubai. UAE. Size: 7 working full time staffs and freelancers when needed. Competitive position: Most luxury lifestyle magazine in the UAE covers the entire GCC region, Elegante focus is to only cover UAE. Target market: Elegante magazines target markets are the UAE high end businesses, segments which includes luxury automobiles, high end fashion and jewelry, 5* hotels, resorts and spas. The magazine is well popular among the youth and business tycoons. Therefore, it targets the big brands name and personalities to increase their sale and brand value. Company performance level: Elegante magazine's sales currently is underperforming and is not being profitable. Main competitors of Elegant are, The Rake, Esquires, and Simply Abu Dhabi magazines. Elegant has a low percentage of repeat clients which is the primary reason for poor financial performance. Therefore, the low performance of the business is affecting it to maintain their market share and customer base. Moreover, the tough challenges from the competitors are hampering the Elegante magazine to maintain its growth rate. In order for Elegant to improve sales and profitability they have to discover the reasons why most clients do not choose to place repeat adverts with them. COUNTRIES LUXURY GOODS (%) UAE 4.89 Oman 4.64 Saudi Arabia 5.17 Qatar 5.24 Kuwait 4.62 Bahrain 4.54 Graph: Percentage of use of luxury goods in GCC (Source: World Economic Forum) It can be understood from the above graph that Qatar is ahead of the other GCC nations in terms of use of luxury goods. Moreover, it can be assumed that in income of people of Qatar is higher than other GCC nations. On the other hand, UAE falls in third place as cost of goods can be high in the country due to which many people may be hesitating to invest for the luxury product. Apart from that, UAE is ahead of other GCC nations such as Oman, Kuwait and Bahrain. Therefore, there is great opportunity for UAE to provide luxury goods to its people so that they can increase their market cap and competitive strongly among the GCC countries. Management Decision Problem (MDP): Should we expand our distribution to cover the entire GCC region? Marketing Research Problem (MRP): To determine how attractive it is to clients if distribution expands to cover the entire GCC region. Components i. What are the benefits of the proposed expansion for clients? Decision outcome: upon completion of our research we will show the benefits offered to clients from expanding distribution to cover the GCC region. The expansion can be valuable for the magazine to reach out to large number of readers and customer circle can be increased. Moreover, the magazine can be able to place itself competitively in the magazine market in UAE and other areas. ii. Who are the clients interested in the expansion Decision outcome: upon completion of our research we will know which UAE clients see Elegant as a better value, when servicing the GCC region. The clients can be able to invest in the magazine that can improve the sale of the magazine in future and it help in generating profit margin. iii. Will there be an audience for Elegant in the new region Decision outcome: upon completion of our research we will have determined if there is a demand for luxury magazines in other regions of GCC. Therefore, it can be considered that Elegante can be able to pull the audience from the new region that can increase their value and visibility in the market. Research Methodology Research Approach The research approach can be effective for the research work so that purpose of the research can be fulfilled. The researcher can go for deductive approach as it can help the work to get accomplish in productive way. The existing theories can be used that can relate to the research paper and it can be modified as per the requirements. Therefore, inductive approach may not be as appropriate as the deductive approach (Bergh and Ketchen, 2009). On the other hand, the researcher may not have enough skills to introduce the new theories or concepts. Thus, the deductive approach can be effective in the practical employment of theories for the particular research paper. Research philosophy (Positivism) The chosen is positivism as subject of philosophy in applications of logic that help analyzing the hidden facts and information in scientific manner. Positivism tries to reject metaphysic so that details knowledge collections in enabled. Positivism is applied in the current context of the study which helps in better analysis of hidden facts and information related to the marketing research process along with consumer buying process (Bernard, 2011). However, nature of the study is time limited so interpretative and realism study is discarded as being the choice of research philosophy. Further, selection of positivism philosophy limits the researcher roles in manipulating or evaluating the data that leads to minimization of data errors as well. Research Design The research approach will be mostly be done in form of in depth interviews conducted with clients and potential clients of Elegant magazine. In addition there will be some quantitative research done to determine the demand and audience for luxury magazines. There will be a combination of exploratory and conclusive research. The clients of Elegant are high end brands and establishments, the point of contacts always are the organizations marketing managers and decision makers. The only feasible approach to our research study will be direct in depth interviews (Bryman and Bell, 2011). As the subjects are professional peers in the marketing field they would be aware projective techniques and trying to use them would come across as disrespectful and will be ineffective. As each of the clients is extremely busy with limited time and specific needs conducting a focus group would also be ineffective. A focus group would be too generalized and time inefficient for this group of professionals. A direct in depth interview will offer a clear and effective means to provide the clients with an opportunity to answer open ended questions, shedding light to complex needs and behaviors. In addition their input will be a great source of information as they would have no reason to hide or mask answers to their opinion on E legant expanding to a wider region. After all every marketer is interested in reducing their CPM (cost per thousand) and would want to be helpful to achieve lower CPM. Clients of Elegant are exclusive high end clients limited in number, catering to the crme de la crme of our society. When dealing with high end people and organizations service becomes a key component to attracting and closing the deal. In order to increase repeat clients for Elegant only in depth interviews can provide the necessary information to adopt strategies and solutions to meet their needs. As the readership of Elegant is the target audience the advertisers will be reaching out to, it becomes relevant to conduct qualitative research to determine the demand for luxury magazines in the rest of the GCC region. Our study will research the luxury consumer market in the rest of the GCC as well as Elegant's main competitors market share and pricing structure. The data on the GCC luxury market will be obtained from industry reports and the pricing structure data will be obtained from primary market research. The research errors will be limited as the qualitative data will come from sources that have vested interest in providing accurate information and the quantitative data will come from reliable secondary sources (Burns et al. 2008). The primary data for competitor information is data available readily to anyone interested in using their services and will be accurate. Exploratory Research Exploratory research was conducted in form of in depth interviews with twelve marketing managers who are the policy makers and project implementers in a two month period. These marketing managers act as gateways to the higher level stakeholders who the final decision power of approving or disapproving the placement of the adverts (Cooper and Schindler, 2010). However on most cases the high level stakeholders rely on the recommendation of their marketing manager for their decision regarding marketing expenditures. Elegant magazine is in a unique position compared to other high volume transaction firms. The current client database consists of approximately two hundred clients with around sixty of them being active clients (Elegant manager). The remaining clients have sporadically placed adverts with Elegant magazine. The advertisement placement cycle is long with Elegant as there are only four issues printed within a year. Due to this long cycle and the relatively small number of clients Elegant magazine sales team has ample time to meet with clients to strategize and follow up. During these meetings a strong and open relationship has been established with the clients, it is due to this relationship that each of the interviewees did not deem it necessary for Elegant to provide a confidentiality clause or consent form. Data sources (Primary and secondary) The study requires only primary sources of informations which helps the topic in extracting the information from the employees of the organizations. The first hand data collection however needs clarification of reliability and validity. In case of secondary data sources , data are used a widening the concept of research that also enables better study of the topic as it involves more data and description (Corbetta, 2009). Primary data includes interaction sections with operation managers who helped in gaining information as per the research objectives. Apart from that, literature sources of the desertions can be considered as output if information gained through secondary sources Primary data sampling techniques Information applications: data gained via topic will helpful in understanding the present trend of the marketing management strategy used by the various organizations. The manager of the Elegant has been chosen for the organizational success. However, any commercial applications of the data will be able avoided so that the findings can be strictly limited to academic purpose only. Respondents participation: The researcher tried to insert no external influence on pressure over the respondents for taking part in the feedback process of the research topic. Respondents with as sense on voluntary participation were encouraged to participate in the following topic (Burns et al.2008). Respondents secrecy: It was ensured that any form if mental or physical harassment was not involved with the respondents so the identity of respondents were covered as per the request for participants (Cooper and Schindler, 2010). Based on the above mentioned list of ethical consideration, the researcher tried to maintain the basic research ethics. Although the Elegant interviewer could have conducted their interview without announcing that they were doing so and the information needed could have been collected as part of their usual meetings, for ethical reasons the client was made aware their responses would become part of a research study and were offered a written confidentiality agreement and consent form. Every interviewee declined the written agreement and was content by verbally asking to remain anonymous. The strength of the relationship and the non sensitive nature of the interview were the reasons why the interviewees were comfortable and willing to share their answers with the Elegant interviewer. The assumption made by the interviewer is that the interviewee will have no motivation to disclose inaccurate information. This assumption is made due to two important and relevant facts, the existing positive relationship and the non sensitive nature of the interview subject. Another fact helping the integrity of the answ ers is the direct benefit to the client by expanding the distribution region which reduces the CPM. From the twelve interviews six were conducted with repeat clients and six with non repeating advert clients. From each group half of the clients have market presence in the GCC region while the other have only operate in the UAE. This sampling was done to cover the four possible combination of client specification. 1 repeat client operating only within UAE market 2 repeat client operating in the GCC market 3 non repeating client operating only within UAE market 4 non repeating client operating in the GCC market Elegant magazine interviewer had 10 questions to explore. The initially factual questions were used followed by opinionated ones, all the questions were open ended and probes were used when necessary. The protocol of the interviews was standardized, informal without using any recording devices. The interviewer used notes with follow up notes after the interviews. The opening and closing of all the interviews were also standardized to maintain a consistent format. In order to answer the three components of MRQ the following questions were asked. The four variations in the question were tailored for UAE only market, GCC market, repeat and non repeating clients. What are the benefits of the proposed expansion for clients? Decision outcome: upon completion of our research we will show the benefits offered to clients from expanding distribution to cover the GCC region. Who are the clients interested in the expansion Decision outcome: upon completion of our research we will know which UAE clients see Elegant as a better value, when servicing the GCC region. Have you found the fact that Elegant only distributes their magazines in UAE as a limiting factor for your marketing needs? Will there be an audience for Elegant in the new region Decision outcome: upon completion of our research we will show the benefits offered to clients from expanding distribution to cover the GCC region. This component used quantitative research. Time scale for the research Figure 1: Gantt chart (Source: created by author) Conclusion The present chapter described the various research tools of selection that can help in better analysis of the topic. With the help of this chapter, the researcher tried to align the nature of the study along with the available research techniques so that possibly the best research methodology is framed. The tools more appropriate to analyse the concepts of present marketing trend for the Elegant magazine. References Bergh, D. and Ketchen, D. J. (2009) Research methodology in Strategy and Management, 1st ed. Bingley: Emerald Group Publishing Ltd Bernard, H. R. (2011) Research Methods in Anthropology: Qualitative and Quantitative Approaches. 5th ed. Plymouth: Alta Mira Press. Bryman, A. and Bell, E. (2011) Business Research Methodology. 3rd ed. New York: Oxford University Press. Burns, R. B., Burns, R. and Burns, R. P. (2008) Business Research Methods and Statistics Using SPSS, 3rd. ed. London: Sage Publications. Cooper, D. and Schindler, P. S. (2010) Business Research Methods, 11th ed. London: McGra-Hill. Corbetta, P. (2009) Social Research: Theory, Methods and Techniques, 4th ed. London: Sage Publications

Cookies vs. Doughnuts Essay Example For Students

Cookies vs. Doughnuts Essay Cookies and doughnuts are both yummy treats, but they also have their advantages and disadvantages. Cookies for instance can be produces with relative ease in any kitchen using flour, water, sugar and eggs. Doughnuts on the other hand are not usually made at home, hence all of the doughnut shops. This is one disadvantage to doughnuts; they are relatively difficult to produce. Doughnuts are made from the same ingredients as cookies, but they also have east in them to give them a more beadlike quality than unleavened cookies. Cookies are traditionally made by combining the ingredients listed and adding something like chocolate or nuts. The cookies are then baked at around 375 degrees for about eight minutes or until they are golden brown. They are then allowed to cool and then they are served. Doughnuts are not as simple as coolies. The dough must be prepared using flour, water, eggs, and then another ingredient; yeast, to add the tiny air pockets that make the dough rise and to make them so edible. After the dough has risen, it can be shaped into the familiar ring shape either by rolling it into snake-like portions or, more commonly, spreading the dough thickly over a flat surface using a device not unlike a cookie cutter. The popular doughnut shop, Krispy Kreme ÂÂ ® has developed a doughnut extrusion process that results in their distinctive rosette shape with curved vertical ridges on the sides. After the dough is shaped, it is cooked using hot oil or fat. This oil is at a much higher temperature than that used to bake cookies. The dough is then cooked to produce a golden-brown crust on the outside while still maintaining a soft core. Sugar may then be applied. This consists of little more than putting sugar and flavoring on the outside of the doughnut in the form of icing, powered sugar, or a glaze which is which is a shell of sugar coating the doughnut. Cake doughnuts are also produced this way using fewer eggs to give them a less airy, more cake-like texture. Adding fruit or nuts to the dough before cooking can change this process, or jelly or custard may be added after cooking through injection. As plainly illustrated, both cookies and doughnuts are sweet indulgences, using familiar flavoring and additives. They also have striking differences such as the cooling methods, and accepted eating times. For instance, people dont think twice about eating doughnuts for breakfast, but no one would feed their children cookies at the same time. After dinner, many people think of cookies and milk as an acceptable dessert, but not doughnuts. While the same in many respects, cookies and doughnuts still maintain a myriad of differences the keep them in their own delicious groups.

Operation Strategy of Coca Cola free essay sample

Coca Cola manufactures More than 21 different brands of beverages from bottled water to a good old coke, the most popular being coke. The Coca cola’s target market is basically everyone. However, their biggest focus are people who fall between he age group of 18-25 that accounts for 40% of the total age segment. In addition, they manufacture beverage for children like Bibo to beverages for older people like coke and soda water. Coca cola tries to satisfy anyone and everyone with the products they manufacture. Moreover, due to the vast target market, it is evident that they need a very large work force. At the end of the company’s fiscal year 2011, coca cola companies total employees was 149 200. On average the turnover for in 2010 the turnover for 2010 was $35 119 Billion according to the annual review. Not Surprising that Coca cola is sold in more than 200 countries in the world. Although, Coca cola is not manufactured in all the countries in the world, it is sold almost everywhere. We will write a custom essay sample on Operation Strategy of Coca Cola or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Coca cola’s ability to anticipate the needs of customers are how they are able to create value for their customers. In addition, the company tries to work closely with chain retailers and small retailers to help them reduces costs and improve sales.As with each successful company, there needs to be some sort of structure. Coca cola’s process flow for bottling coke is as follows; 1. Ingredients are delivered to the factory 2. New and old bottles are sort into the various sizes 3. The bottles are then washed in a special detergent 4. Afterwards, the bottles are inspected, visually to ensure they are clean 5. All the cracked and chipped bottles are removed and destroyed 6. Each bottle is then electronically inspected to ensure they meet the standard 7. All faulty , cracked, chipped or dirty bottles are removed and destroyed 8.Then the mixing and blending of the syrup takes place 9. Syrup is the mixed with concentrate 10. And then with carbonated water 11. The bottles are then filled with the liquid 12. And are then capped 13. Bottles are only then labeled 14. After the bottles have been labeled, they are coded 15. The final inspection of the products takes place before packaging 16. Then the bottles are packaged according to the size and the bottle 17. After which the products are sent to the warehouse 18. Stock is rotated to ensure freshness 19. The products are then delivered to retailers 20. Lastly, products are sold to consumers. Component 1: Process Flow We have identified that Coca Cola makes of a Continuous Process flow which allows them to produce more standardized products in a high volume. Below we will graph the process flow of the Coca Cola company and then elaborate more on the components which makes up their processes. Component 2: Operations Strategy According to Slack and Lewis, Operations strategy is the total pattern of decisions which shape the long-term capabilities of any type of operations and their contribution to the overall strategy, through the reconciliation of market requirements with operations resources.With the given definition of operations strategy we will also identify the competitive priorities of the Coca Cola company and how it relates to the above mentioned definition. Competitive priorities of an organisation includes a) low cost, b) high quality, c) fast delivery, d) flexibility and e) service. Operations strategy also depend on order qualifiers and winners, which relates to requirements for success in the market place. The above mentioned priorities are not always the same for every company. Coca Cola may have different customer requirements then the next company. Therefore we have spoken to some customers who are buyers of the Coca Cola company as well as interviews with employees to see whether their opinion of customer requirements relates to what the actual customer wants. Coca Cola’s view on customer requirements: Customers and their requirements from the Coca cola company: Based on the research we have done regarding the customers requirements for the Coca Cola company we have find that they are very specific in what they require from the company.When we talk about customers of Coca Cola we don’t just talk about the customer that walks into the retail shop and buy a few quantities of the product. We are more focused on the retailers, the restaurants and the small businesses that buy this product in bulk. So when we are focusing on the customer requirements we look into what it is that they expect from the Coca Cola company. As our findings have showed , these customers are always seeking ways to reduce costs, improve/increase sales as well as provide better quality and more diverse products to the consumers who in the ends decide whether the product meets their needs or not. Coca Cola works together with their customers trying to meet their anticipating demands and interests and to proactively deliver solutions to their businesses. As above stated, one can see that the customers (small business, restaurants and retailers) of the Coca Cola company are demanding in what they want as they also have consumers to satisfy. If the customers demands are not met then the consumer Component 3: Operational Capabilities Location Location is the geographical area where a given business is situated at . Depending on the location, the business may either be successful or unsuccessful.The business is situated in Parow, 57 Industria, Ring Road and the reason for chosen this specific Coca Cola manufacturer as it is close enough for us for interview purposes. I will now discuss the reasons for having the manufacturing business in such an area and whether the location is suitable enough for its given operations. Peninsula Beverages is a franchise Manufacturing company that operates under the name of Coca Cola. As previously stated, they are situated in Parow Industria where the manufacturing takes place.

Every AP Biology Practice Test Available Free and Official

Every AP Biology Practice Test Available Free and Official SAT / ACT Prep Online Guides and Tips Practice tests can help you get familiar with the structure of the AP Biology examand feel more comfortable with the types of questions you'll be expected to answer on test day. Studying with practice tests can also give you insight into the specific struggles you might have with the material as presented on the AP test. You can then focus your studying appropriately to tackle these problems. In this article, I'll list all the practice tests for AP Biology that you can find online and give you a few tips on how to use them effectively as study aids for both the AP test and any in-class tests you have throughout the school year. Official AP Biology PracticeExams Official practice tests provide the best preparation for the AP test.You can be sure that the questions are accurate representations of what you'll see on the final exam. Unfortunately, I could only find one official practice test for the new version of the AP Biology test since the format and content changed so recently (2012).However, this practice test also has other information that makes it more helpful. It tells you how to calculate your score and includes detailed answer explanations for each question at the end. Official Practice Test #1 Don't start your practice with this test. It's the most accurate preparation you'll have forthe real AP test, so you should save it for towards the end of your second semester when you feel confident that you've mastered the material. It's better to begin studying with the unofficial tests in the next section as a warm-up! You can also access official free-response questions from 2013, 2014, and 2015 on the College Board website. Free Response Questions The free-response section of the AP Biology test is usually considered to be the most difficult part, so it’s good to have a little extra practice with these even if you’re not answering them in the context of a full practice test. In addition to these resources, all AP teachers have access to a bunch of free official practice AP tests online. You can ask your teacher if he or she will print a couple out for you to use in your studying. It might take more than one apple to get those extra practice tests out of your teacher, but ultimately everyone has a price. Want to get a perfect 5 on your AP exam and an A in class? We can help. PrepScholar Tutors is the world's best tutoring service. We combine world-class expert tutors with our proprietary teaching techniques. Our students have gotten A's on thousands of classes, perfect 5's on AP tests, and ludicrously high SAT Subject Test scores. Whether you need help with science, math, English, social science, or more, we've got you covered. Get better grades today with PrepScholar Tutors. UnofficialAP Biology PracticeExams There are many unofficial AP Biology practice tests out there that you can use to help review the material.There’s nothing wrong with using these tests to get more practice, but try not to rely on them exclusively because they are not always totally accurate representations of the real AP Biology exam.Some are aligned with the format of the pre-2012 exam, and some are just multiple-choice tests of varying lengths with no free response questions. Because the AP Biology exam has been revised, you'll get a more accurate estimate of how well you're doing if you use recent practice tests that are aligned with the new test's format. Before 2012, the AP Biology testhad 100 multiple-choice questions and four free-response questions rather than the current 63 multiple-choice questions, six grid-in questions, six short free-response questions, and two long free-response questions. The old test was also more memorization-based. On the current AP Biology exam, you'll have to answer a lot of questions that involve analyzing experimental data using your background knowledge of biology. You won't see questions that just ask you to do something like identify parts of a process in a diagram. A couple of these unofficial tests do have the same format as the current exam, including the Barron's practice test and all the tests in the "subscription needed" section. You should save these for later on in your second semester when you want to get a more accurate assessment of your readiness for the final exam (and then follow them up with the official practice test in the previous section if you feel confident that you've fixed your problem areas!). Free AP Biology Practice Tests Barron’s Practice Test Barron’s offers a free practice test online that has the same format as the current AP test. You can take it in timed or untimed (â€Å"practice†) mode. If you use practice mode, you can see answer explanations as you go along. The multiple-choice section has automated scoring, but you’ll have to self-score your free-response answers (guidelines are provided). My Max Score Practice Test This is an old-format test that includes 100 multiple choice questions and four free-response questions. It also has detailed answer explanations for all questions. Varsity Tutors Diagnostic Tests This is a list of ten multiple-choice diagnostic tests rated by difficulty level. Tests 4-10 have the same number of questions as the real multiple-choice section. Sorry, there are no free-response questions on this site. Kaplan Practice Tests There are a few unit-specific quizzes here along with two longer practice tests that have almost as many questions as the multiple-choice section on the real exam (58 and 62 as opposed to 63 + 6 grid-ins). There are no free-response questions. Learning Express 120-Question and 100-Question Practice Tests These are a couple more old-format multiple-choice tests with answers included at the end. If you just want to test yourself on the basic information in the course, these could be useful. Subscription Needed Shmoop Practice Tests (free trial available, $24.68 a month for subscription) A subscription to Shmoop will get you access to a diagnostic test plus five full AP Biology practice tests (including both multiple-choice and free-response questions, although these are of course unofficial). Shmoop tries a little too hard to relate to kids with their writing style, but if you're not put off by that, it might be a good resource for you. BenchPrep Practice Tests (with subscription that costs $30 a month) Here, you’ll get access to two full practice tests plus a ton of lessons. Practice Tests inReview Books You might also decide to order a review book to get access to more practice tests. You'll find some good resources in the books listed in my article on the best AP Biology books for 2016. Make sure you have some nice fresh erasers cuz your pencils are in for a wild ride across the treacherous terrain of the AP Biology curriculum. Wooohooooo! How to Use AP Biology Practice Tests This section is full of all the advice you need to follow to use AP Biology practice tests effectively during both your first and second semesters in the class. First Semester: Using Practice Tests for Your Class Although it might not make sense to take full practice tests yet, you can still use the materials in this article as resources for your studying.Look for free-response questions that relate to what you’ve learned so far so that you can start to get familiar with their format and expectations. There are also plenty of sites that have quizzes that touch on specific units in the AP Biology curriculum.These include Learnerator, Varsity Tutors (which I mention above for diagnostic tests, but they also have subject-by-subject quizzes), and Quizlet.These won’t be official questions, but they will help prepare you for in-class assessments and serve as a solid introduction to the types of questions you might be asked on the AP test.You should also check out my complete AP Biology review guide for more advice on how you can use online resources to study specific units of the course. Second Semester: Preparing for the AP Test By this time, you should be familiar with most of the material that you’ll see on the test.This means you can start using full practice tests to judge how you’ll score on the AP test and where your weaknesses lie.Remember to time yourself accurately when you take practice tests!Each time you take and score a practice test, you should also do an evaluation of your mistakes that will inform your studying going forward.Mistakes come in a few different forms, and things can be even more complex on the AP Biology test because there are technically four types of questions. Focus on the multiple-choice section first, including the grid-ins.Notice whether your mistakes tend to happen on straightforward questions where you just didn’t have the content knowledge or on questions that require deeper analysis.Were there specific content areas where you missed a significant number of questions?Keep track of this so that you can go back into your notes and review the appropriate unit(s).These are easy mistakes to fix. Did you have trouble interpreting and analyzing scenarios on the test even though you knew the background information?The remedy for this is more practice. There are many sites with AP Bio practice questions available.This book of practice questions is also useful because the questions faithfully replicate the new design of the test. It’s possible that your problem lies outside the specifics of the questions and more in the format of the test.Did you run out of time? Make a ton of careless mistakes?The solution to this is greater awareness of your pacing and more practice questions. Careless mistakes can be avoided by greater awareness of your surroundings. Also, how did someone even fit that big of a gum wad in their mouth? Was a giant chewing gum in this parking lot? Should we be concerned about his current location? I have a lot of questions. Grid-ins are weird, so you may have had trouble on them if you’re not big on the math aspect of biology.Try to find similar problems in your textbook, review book, or online so that you can practice your skills.The more math-oriented biology questions you do over time, the more likely it is that the questions on the test will be aligned with what you’ve already seen. After taking your multiple-choice mistakes into account, you can move onto the free response section.Notice which questions gave you the most trouble and why.Did you forget the information you needed, or were you confused about what the question was asking or how to analyze a diagram?Take these findings and apply them to your future practice! Essential AP Biology Practice Testing Tips Follow these four tips to be sure to get the most out of your AP Biology practice tests. #1: Replicate Realistic Test Conditions It’s always important to be faithful to the rules of the real test when you take practice tests so that your scores accurately reflect your potential.That means an hour and thirty minutes for each section.This is the only way to judge whether time is going to be an issue for you.You should also print out the test so that you take it in the right format. Have a calculator on hand as well.If you’re really dedicated, you can even have someone serve as your mock proctor. #2: Don’t Panic if You’re Not Familiar With Scenarios You See on the Test Even if you’ve gone over every in-class lab that you had to do for AP Biology, you will still run into examples you haven’t seen before.It’s important not to psych yourself out when this happens.Focus on the diagrams and what you can learn from them, and see if you can think of a related experiment that will clue you into what they mean.Use your common sense; many questions will depend more heavily on your ability to analyze the situation at hand than on your memorization talent. #3: Give Yourself Plenty of Time for the Grid-Ins The so-called multiple-choice section also includes six grid-in questions.These questions are at the end of the section, and they will probably take you longer to solve than most multiple-choice questions.Try not to spend more than a minute on each multiple-choice question.If you find that you’re taking too much time, you should move on and come back to it later! #4: Spend 5-10 Minutes Reading the Free-Response Questions Before You Start Writing It’s a smart idea to start with the free-response questions that you know you can answer quickly and accurately. Leading with these questions will boost your confidence and help you avoid problems with time.Use the short reading period to look over all eight free-response questions and see which ones will be easiest for you to tackle. For example, I would definitely answer a question about snails first. I love snails. My pet snail died not too long ago, and I'm scared to get another one because I don't want to feel that pain again. Want to get a perfect 5 on your AP exam and an A in class? We can help. PrepScholar Tutors is the world's best tutoring service. We combine world-class expert tutors with our proprietary teaching techniques. Our students have gotten A's on thousands of classes, perfect 5's on AP tests, and ludicrously high SAT Subject Test scores. Whether you need help with science, math, English, social science, or more, we've got you covered. Get better grades today with PrepScholar Tutors. Conclusion You should take plenty of practice tests as part of your studying for AP Biology.You can’t expect pure memorization to save you on questions that ask you to analyze scenarios you’ve never seen before. Practice questions are the key to improvement! You can use a mixture of official and unofficial tests to practice. Just be wary of major differences in your scores from test to test so that you can accurately assess your readiness for the final.You can even use these tests throughout the year to practice for specific units of the course.If you do enough serious practice, the real AP test will be a piece of cake (well, maybe not, but it will be much less traumatizing). What's Next? Check out my detailed guide to the AP Biology Exam for more information about what's on this test and how you can prepare for it. Are you taking both AP tests and SAT Subject Tests? Find out which kind of test is more important and what the major differences are between the two. Many students take AP classes in the hopes of earning credit for college coursework in high school. Learn more about how AP credit works in college. Want to improve your SAT score by 240 points or your ACT score by 4 points?We've written a guide for each test about the top 5 strategies you must be using to have a shot at improving your score. Download it for free now: